around the same dmg potential with a fully optimized setup (on par with WotW, CoE, Zodiac), but needs ridiculous amounts of determination (nobody will every do this, not even myself xD )
still it got more toughness due to Aquila and therefor maybe just maybe could even clear a bit higher.
dmg output theorycraft:
LoN set bonus (1300%) vs WotW + CoE set bonus (1200%) = +8,33% LoN
66% WotB uptime vs 100% WotB uptime = +~25% WotW
30% Attackspeed Bul Kathos Set or Istavan = +~30% WotW
Hexing Pants = +~12,5% LoN
Doombringer 20% Physical = +~14,2% LoN
Witching Hour = +~12% LoN
Pain Enhancer (~0-50% very situational) vs Trapped (~45%) = +~20% LoN
on top WotW can have more Area Dmg on Gear, LoN benefiting more from double dip in Bloodshed (more Physical). Very hard to estimate who would come on top dmg wise, cus it mainly depends on reaching certain breakpoints (ATS rolls on LoN gear, Lacunis, Witching hour, both weapons, maybe gloves to reach another breakpoint).
WotW clears crazy density argueably a tiny bit faster faster (cus of Pain Enchancer + more AD vs Trapped + better Bloodshed)
LoN kills the RG ~50% faster and can finish off smaller packs much smoother.
So the main benefit from a fully optimized gear is:
1) aquila buff
2) more freedom in choosing skills, easier to play since you dont need to keep track of obsidian management.