When I finally hit 60 (56 and 4 bars from 57 now) I'll get 2 weapons with the same DPS rating and INT amount and test if it affects damage from hydra or blizzard. I'll probably use regular hydra and not venom though since those numbers should be more consistant since I won't be looking at stacking pools.
EDIT: I'm super late didnt see that there were 5 pages here. But some extra calculations to look over none the less since some people are not fully understanding.
I must confess the way you are calculating this is a bit strange because you are using two different constants for two different variables. But if we look at this this way:
Weapon A: 100 DMG, 1.0 A/S
Casting ray of frost (unmodified) for 10 seconds [100+(10xT)-(20xT)=0 where T=time (in seconds)=10] you run out of mana and get
1(100x2.15)x10=2150 damage in 10 seconds
A(DxM)xT=Total
A = Number of attacks a second
D = Base damage of weapon
M = Damage modifier on spell
T = Time spent attacking
Weapon B: 50 DMG, 2.0 A/S
Casting ray of frost (unmodified) for 3.33 seconds (rounding to 3 though) [100+(10xT)-(40xT)=0 where T=time (in seconds)=3.33] you will run out of mana and get
2(50x2.15)x3=645 damage in 3 seconds
BUT!
With 7 seconds left over you can cast magic missle 14 times at 115% modifier for 14(50x1.15)=805 extra damage brining the total to 1450 damage and have 70 mana at the end.
Then we can see your point.
In the end Weapon A will do more damage because players have more time to use a spell with a higher damage modifier. When we calculate spells like disintegrate with the rune that causes mobs to have a chance to explode at 315% (I believe) weapon damage we can see an even bigger overall DPS increase. However, should you ever have a choice between two weapons with the same damage but one that attacks faster, you should choose the faster one because over a period of 10 seconds you will still end up with more damage even with using lower damage modifer spells.
(I bolded text to help people read what I was saying to avoid confusion.)
Now since we have arrived at this conclusion, it was the OPs original point that by modifing the ray of frost with lower mana cost/second you can successfully cast it for longer over that 10 seconds and thus raise your total DPS over 10 seconds with a faster swinging weapon.
At this point however, since you were equipping runes to be optimal, he presumed that the person not having AP management problems would equip a rune to increase the spell damage modifier on ray of frost brining you to his original calculations.
From there he then expanded into the idea that using a higher delay, slightly lower DPS, weapon would be more beneficial for most players since they commonly use spells like disintegrate and hydra.
The only problem is the OP seems to have skipped sharing some of that in his first post.
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I must confess the way you are calculating this is a bit strange because you are using two different constants for two different variables. But if we look at this this way:
Weapon A: 100 DMG, 1.0 A/S
Casting ray of frost (unmodified) for 10 seconds [100+(10xT)-(20xT)=0 where T=time (in seconds)=10] you run out of mana and get
1(100x2.15)x10=2150 damage in 10 seconds
A(DxM)xT=Total
A = Number of attacks a second
D = Base damage of weapon
M = Damage modifier on spell
T = Time spent attacking
Weapon B: 50 DMG, 2.0 A/S
Casting ray of frost (unmodified) for 3.33 seconds (rounding to 3 though) [100+(10xT)-(40xT)=0 where T=time (in seconds)=3.33] you will run out of mana and get
2(50x2.15)x3=645 damage in 3 seconds
BUT!
With 7 seconds left over you can cast magic missle 14 times at 115% modifier for 14(50x1.15)=805 extra damage brining the total to 1450 damage and have 70 mana at the end.
Then we can see your point.
In the end Weapon A will do more damage because players have more time to use a spell with a higher damage modifier. When we calculate spells like disintegrate with the rune that causes mobs to have a chance to explode at 315% (I believe) weapon damage we can see an even bigger overall DPS increase. However, should you ever have a choice between two weapons with the same damage but one that attacks faster, you should choose the faster one because over a period of 10 seconds you will still end up with more damage even with using lower damage modifer spells.
(I bolded text to help people read what I was saying to avoid confusion.)
Now since we have arrived at this conclusion, it was the OPs original point that by modifing the ray of frost with lower mana cost/second you can successfully cast it for longer over that 10 seconds and thus raise your total DPS over 10 seconds with a faster swinging weapon.
At this point however, since you were equipping runes to be optimal, he presumed that the person not having AP management problems would equip a rune to increase the spell damage modifier on ray of frost brining you to his original calculations.
From there he then expanded into the idea that using a higher delay, slightly lower DPS, weapon would be more beneficial for most players since they commonly use spells like disintegrate and hydra.
The only problem is the OP seems to have skipped sharing some of that in his first post.