Very vague but you should be able to survive mp10 just fine with those stats unless there is more to the story...like what you are getting hit by. My stats are 53k health, 5.8% lifesteal, 640 all resist, and 315k unbuffed dps..I can carry mp10 ubers with those stats so you shouldn't be having two shot issues unless you mean just standing there and letting the high damage enemies get free shots
For reference http://us.battle.net/d3/en/profile/Sheol-1663/hero/1954735
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900+ all resists for a barb would be a bit of overkill and honestly not even worth trying to achieve unless accomplished naturally with insane gear
For reference http://us.battle.net/d3/en/profile/Sheol-1663/hero/1954735