My current spec. I'm in a3 NM, and so far, it's been so easy (minus a few elite/rares with bad combos who 2 shot me when I'm not paying attention). I have a 2h and a 1h/shield combo(for prior elites).
I switch around my spec all the time just to see if I can get things better.
Just go to the AH, look for a good 2h rare weapon for 1.5k > 5k gold. There are lots out there, go for str/vit/life leech imo. DW has been rather unsuccessful for me so far (most skills use main hand damage and make your OH practically worthless)
Pretty much what i used for all inferno (WW first was with heal on crits, and then i changed +5% crit to +dmg if 3+ mobs are there) http://us.battle.net/d3/en/calculator/barbarian#ahYVkT!ZYd!aYZbbb
you normally start with shout then WW in to the group and then stun and WW+Revenge on proc\EQ by cd. /i tried Juggernaut, but its never procc'ed for me and i kinda don't like (don't see great affect from ignore pain)
ps. my character have ~5% of vampiric and 130-140 life on hit.