I can't see a reason why offensively this won't work. But, I can see too many reasons why defensively this absolutely won't work. I don't see Inferno difficulty being easy enough to completely avoid the majority of the defensive skills available. And considering that it will take some time to gear up your resistances and leech high enough to even try to manage a glass canon build, this seems like a build that won't even get off the ground.
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