Thing is that those who have alot of dmg go glasscannon build, don't go any def at all.. so
My vitality build which is required to solo azmodan and first boss in act 4 has:52k HP190 phys resisAround 60O all Resist. I get 1 shotted by EVERYTHING still so its kind of pointless. Better to kill them before they kill you.
Stats:
1850 dex
137 percent crit dmg
106 percent IAS (2x 14 rings, 12 amulet, 12 helm, 16 quiver, 12 bracer, 14 gloves,12 weapon)
1083 dps xbow
I'm on Diablo now on inferno.