But yes, classes do work together - usually a main DPS character to deal out damage - sometimes 2, one for the Rift Guardian other for the mobs. And then you'll have support characters to keep the DPS guys alive.
So WD, Wizards, Necros and DH have been main DPS.
Barbs, Monk, Necros, and Crusaders have been supports.
But you can make any character a DPS or Support.
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I wouldn't say combo as in it becomes a new move.
But yes, classes do work together - usually a main DPS character to deal out damage - sometimes 2, one for the Rift Guardian other for the mobs. And then you'll have support characters to keep the DPS guys alive.
So WD, Wizards, Necros and DH have been main DPS.
Barbs, Monk, Necros, and Crusaders have been supports.
But you can make any character a DPS or Support.