Seems to me that Aura of Frailty is providing you with a fairly static ~17% damage increase having things die after 85% of their HP has been removed, while a corpse fueled poison skill like Corpse Explosion (Close Quarters) or Corpse Lance (Ricochet) would provide a 33% damage increase by adding a 4th stack of Nayr's.
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Seems to me that Aura of Frailty is providing you with a fairly static ~17% damage increase having things die after 85% of their HP has been removed, while a corpse fueled poison skill like Corpse Explosion (Close Quarters) or Corpse Lance (Ricochet) would provide a 33% damage increase by adding a 4th stack of Nayr's.