I would argue that Cascade is superior to Disruption mostly in pack clearing. Just because the proc'd missile cannot hit the target it was proc'd on. This makes Disruption the de facto superior option against single targets. Cascade will do better against Elite packs and generally for clearing. And as you mentioned, Disruption is very useful in group situations, so I consider it the more utility-orriented rune of the 2. The difference is not (in my experience) substantial between the two runes, so it really depends on what you're looking for out of your build. So I wouldn't call one rune superior to the other per say, they just have different uses.
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A wise man once said: "The problem with common sense is that it's just not that common..."
So apparently I was gravely misinformed about the Cascade rune... Thank you Helycon for correcting me on that point. Now that I have a more... correct understanding of the rune, I've been using it for the previous 2 days to get a good feel for it. Overall, I find the single target damage between the 2 runes to be very very similar and of course Cascade wins out in AoE situations handily (just from my personal observations). That being said, I will be changing the guide to reflect my new preference on Cascade over Disruption and detail when you might consider taking Disruption (ie: party situations). Once again, thank you for pointing this out.
Sincerly,
A noob.
Beelzeuhb: that's the essence of many builds, you'll find many of them operate in this way, at least until you get some decent gear, then options open up such as builds without a signature spell. This particular build can easily operate without a sig spell, but it does take either some above average gearing, extra emphasis on AP generation in your skills or a slower weapon. This is of course if you're willing to drop AD, which is a fair hit in damage potential.
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A wise man once said: "The problem with common sense is that it's just not that common..."
http://us.battle.net/d3/en/profile/METD-1485/hero/1750126
Sincerly,
A noob.
Beelzeuhb: that's the essence of many builds, you'll find many of them operate in this way, at least until you get some decent gear, then options open up such as builds without a signature spell. This particular build can easily operate without a sig spell, but it does take either some above average gearing, extra emphasis on AP generation in your skills or a slower weapon. This is of course if you're willing to drop AD, which is a fair hit in damage potential.
http://us.battle.net/d3/en/profile/METD-1485/hero/1750126