In 2.6.1 Natalya's Vengeance got buffed a lot and it's now competitive with the other top DH builds again, going up to around Tier 110 in endgame pushing.
The main variation of this build runs Lightning FoK and Fire RoV. Optimize your gear for FoK since RoV is mainly there to proc the 6pc bonus, spawn Oculus rings and just do some bonus damage. The big burst comes from your Fan of Knives explosions.
Besides the main build, there is also one variation with pure Rain of Vengeance, however it will be a few tiers weaker, and a Shi Mizu version, which will be a little stronger and probably become the strongest DH solo pushing build in season 12. The Shi Mizu version is very difficult to play and also requires very optimized gear and high paragons to be worth.
If you are not familiar with the playstyle of a Natalya build, I strongly suggest to watch the video. I cover the skill / item choices and gameplay in more detail there.
N6 can also be played as a farming build, however it's no match for the equally buffed UE Multishot.