Blood Regen Madness (GR85+)

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  • Grim Scythe Cursed Scythe
  • Death Nova Blood Nova
  • Bone Armor Thy Flesh Sustained
  • Land of the Dead Frozen Lands
  • Blood Rush Transfusion
  • Corpse Explosion Final Embrace
  • Eternal Torment
  • Stand Alone
  • Draw Life
  • Blood is Power


More Details
  • Legendary Gems

    • Esoteric Alteration
    • Molten Wildebeest's Gizzard
    • Bane of the Trapped

Kanai's Cube

  • Reilena's Shadowhook
  • Grasps of Essence
  • Obsidian Ring of the Zodiac

Paragon Priorities


Movement Speed
Primary Stat
Maximum Resource


Cooldown Reduction
Critical Hit Damage
Critical Hit Chance
Attack Speed


Life Regeneration
Resist All


Area Damage
Life on Hit
Resource Cost Reduction
Gold Find

Build Guide

-Some vitality rolls have been replaced with Life Per Second to have the most effective healing possible,
It should be close to 500k Life Per Second with bone armor up + 10 mobs nearby, with a total health (including 4pc bonus) of around 850k you'll heal to full life in 1,5secs.

-Max Cooldown reduction is also a must so Land of the Dead can be up as much as possible for 300% increased damage from Krysbin and allowing you to spam Corpse Explosion.

-Simulacrum was removed for Corpse Explosion, the previous version was wasting corpses and having two 120secs skills was making us take too long resetting cooldowns (and it looks really bloody which is the entire theme of this build).

-Leoric's Crown in cube was also changed to Grasps of Essence since we can now reset the cooldown on land of the dead much faster and it gives a nice boost to corpse explosion.

-Scythe of the Cycle was changed since it doesn't buff Corpse Explosion, Reilena's Shadowhook was added instead to buff all our damage, so remember to have max essence in the weapon and shield.

-Land of the Dead rune has been changed to Frozen Lands to maximize Krysbin's damage and allowing you to switch bracers to Ancient Parthan Defenders since frozen works with those bracers.

-I also tried a variation changing Corpse Explosion for Corpse Lance and equipping Corpsewhisper Pauldrons in the armor slot for the cube, it cleared 80+ also, but it's a lot more single target so you have to hunt more elites and it's not as bloody themed as this variation, but it definitely has potential.