I also pick every rare item and any gold piles over 2k but Im considering to remove some items from my pick-up list. I need to clear my inventory at least 2 and sometimes even 3 times per my extended run. I die rarely, usually I blow myself up against reflect damage pack where I miss health link affix or I jump into molten bomb when trying to pick up rares from the ground.
My extended full-pick up run takes me between 30 to 35 minutes now. I will time original Alkaizer without picking rares/gold tonight and post my results--I assume I should get it down to 15 minutes or so on MP2.
PS. I prefer ranged mobs elites/champions, spearman or archers are my favourites, becuase they tend to stick together at start, which is enough time for me to blow them in 2 or 3 CA into smithereens.