Kind of a tricky question.
For Rimeheart to proc, you need to hit frozen enemies - which is not a big problem with Wizard due to Frost Nova/Halo of Arlyse or other skills. I can see a setup using Ice Blades for more chance to freeze people, maybe adding an Iceblik gem to make the blades chill everyone automatically.
However, there are some fundamental flaws on this (and it's not Iceblink though it's a big hit on damage).
First of all DMO doesn't buff all character damage but only some specific skill damage. So while with an Ice Blades setup you could potentially deal quite some damage, Rimeheart damage isn't actually buffed. Basically, it's not another Manald Heal until you use Tal Rasha (the set buffs all damage including Manald Heal, that's the reason why TR/Archon/MH was strong in S9 and why it is in S10 with Hydras).
Second, Rimeheart procs on freezed targets - which is bad, because of diminishing returns on CC which hits the uptime of freeze pretty hard. While you can theoretically spam freeze around you, the actual time the targets are freezed is much lower, thus hitting hard the Rimeheart proc. MH is so strong because it procs from a passive and doesn't matter of the stun connects or not, the damage will still be triggered ignoring the CC diminishing return.
TL;DR: DMO with Rimeheart may work, but the performance won't be good, mostly because Rimeheart is a bad proc mechanic compared to a similar item (Manald Heal)