The welcome death of the Auction House simply means the welcome death of trading in D3, which makes the game a children's game and having no end game at all after killing the end boss. TLDR: the end of playing Diablo 3 endlessly.
MUCH better games around than going 4 times through the same boring story cycle in a useless grind as you only play by yourself.
So aside from farming for content, what end game was there in D2? Ladders were not there off the start, they were added in later.
WIth your bountys and rifts and adventure mode we already have more end game. Ladders will come, if its not right at realease of the expansion so be it.