It could be that I'm just lazy, but I would really like to see an AoE loot pickup option added within the game. It could work as follows:
You go into the settings to enable AoE Looting. You get to choose what options get looted between common, magical, rare, legendary, set, gems, crafting, and potions. Then, as you play, you can click on one of the dropped items within the options you selected and pick-up all of those items within 25 yards.
Am I the only one that would like this in-game?
(As a side note, I would also like to see an mass vendoring and mass salvaging.)