I found this chest in the same place today three times in a row, so I decided to share with you guys.
In Act II Blood and Sand quest you get the waypoint for the desolate sands.
If you get the right layout of the map, you should see a giant circle with a resplendent chest south of the waypoint, the chest is protected with a giant twister, when you approach it, it will start spawning sand dervishes around the circle, about 8-12 dervishes will spawn, when you're finished with them the twister will dissipate and you will be able to open the chest.
In Act II Blood and Sand quest you get the waypoint for the desolate sands.
If you get the right layout of the map, you should see a giant circle with a resplendent chest south of the waypoint, the chest is protected with a giant twister, when you approach it, it will start spawning sand dervishes around the circle, about 8-12 dervishes will spawn, when you're finished with them the twister will dissipate and you will be able to open the chest.