Unless you plan to focus on a Calamity-only build, attack speed is necessary. Even with Calamity I know high-DPS DH's that don't avoid IAS. With Manticore you want more IAS. The argument that it wastes Hatred is flawed-only shoot the same number of Skill "X" and you'll be using the exact same Hatred as with less IAS. The question about Run Speed is beyond belief; of course you want high Run Speed.